The South-East Asia Region: Societal Conditions for LGBT Health and Cancer Research

This chapter is a substitute for chapters that were not completed due to the COVID-19 pandemic. In lieu, this chapter on LGBT and cancer in the South-East Asia region provides an overview of recent changes in sexual and gender minorities' legal situation, various aspects of LGBT communities, and organizations. While cancer is recognized as a threat to the region, a literature review of LGBT health research shows that a wide range of different topics are explored, with infectious diseases being the main focus. The time appears right for an expansion of the scope of LGBT health research to more prominently address noncommunicable diseases, such as cancer. However, it might be possible that COVID-19 will further delay research on noncommunicable diseases among LGBT populations. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Time trends and COVID-19 post-pandemic changes in physical activity and sedentary behavior prevalence among Brazilian adults between 2006 and 2021 / Tendências temporais e mudanças pós-pandemia de COVID-19 na prevalência de atividade física e comportamento sedentário em adultos brasileiros entre 2006 e 2021

ABSTRACT Objective: To analyze time trends and prevalence of physical activity and sedentary behavior among adults of Brazilian capitals between 2006 and 2021, including the pandemic period. Methods: This is a time-series of cross-sectional surveys based on the National Surveillance System for Risk and Protective Factors for Chronic Diseases by Telephone Survey. Trends of sufficient leisure-time physical activity, sufficient physical activity while commuting, insufficient practice of physical activity, and total screen time were estimated by using Prais-Winsten regression. Annual prevalences and time trends were estimated for each indicator by sex, age group and education. Results: For total population, significant time trends were found for leisure-time physical activity (β=0.614) and total screen time (β=1.319). As for prevalence, leisure-time physical activity increased from 29% in 2009 to 39% in 2019, followed by a reduction of 2.3% between 2020 and 2021. Total screen time prevalence increased considerably between 2019 and 2020 (4.7%). Though physical inactivity tended to reduce along the series, its prevalence increased by 3.4% between 2019 and 2021, as well as physical activity while commuting decreased by 3,7% in the same time period. Conclusion: Whereas leisure-time physical activity increased over the years, it is uncertain whether this trend will be the same in the years following COVID-19. Not only did people alter their leisure-time habits, but also there was an increasing dominance of screen time due to the change in work and social patterns. More strategies need to be addressed to tackle physical inactivity and sedentary behavior, and to review the post-pandemic national targets.

RESUMO Objetivo: Analisar as tendências temporais e a prevalência dos indicadores de atividade física e comportamento sedentário em adultos das capitais brasileiras entre 2006 e 2021, incluindo o período de pandemia. Métodos: Trata-se de estudo de série temporal de inquéritos transversais baseado no Sistema de Vigilância Telefônica de Doenças Crônicas. As tendências de atividade física suficiente no lazer, atividade física suficiente no deslocamento, prática insuficiente de atividade física e tempo total de tela foram estimadas por meio da regressão de Prais-Winsten. As tendências temporais e as prevalências anuais foram calculadas por sexo, faixa etária e escolaridade. Resultados: Na população total, foram encontradas tendências temporais significativas para atividade física suficiente no lazer (β=0,614) e tempo total de tela (β=1,319). Quanto à prevalência, a atividade física suficiente no lazer aumentou de 29% em 2009 para 39% em 2019, seguida de redução de 2,3% entre 2020 e 2021. A prevalência do tempo total de tela aumentou consideravelmente entre 2019 e 2020 (4,7%). Embora a inatividade física tendesse a diminuir ao longo da série, sua prevalência aumentou 3,4% entre 2019 e 2021, assim como a atividade física no deslocamento diminuiu 3,7% no mesmo período. Conclusão: Enquanto a atividade física suficiente no lazer aumentou ao longo dos anos, é incerto se essa tendência se manterá nos anos seguintes à COVID-19. Não apenas as pessoas alteraram seus hábitos de lazer, mas também há um domínio crescente do tempo de tela em razão da mudança nos padrões sociais e de trabalho. Mais estratégias precisam ser abordadas para o enfrentamento da inatividade física, do comportamento sedentário e para a revisão das metas nacionais pós-pandemia.

Temporal trends of morbidities, and risk and protective factors for noncommunicable diseases in elderly residents in Brazilian capitals / Tendências temporais de morbidades e fatores de risco e de proteção para doenças crônicas não transmissíveis em pessoas idosas residentes nas capitais brasileiras

ABSTRACT Objective: To analyze the temporal trends of prevalence of morbidities, risk and protection factors for noncommunicable diseases in elderly residents in Brazilian capitals between 2006 and 2021. Methods: A time series study with data from the Surveillance System of Risk and Protective Factors for Chronic Diseases by Telephone Inquiry. The variables analyzed were: high blood pressure, diabetes, smoking, overweight, obesity, consumption of alcoholic beverages, soft drinks, fruits and vegetables, and the practice of physical activity. Prais-Winsten regression and Interrupted Time Series from 2006 to 2014 and 2015 to 2021 were used. Results: From 2006 to 2021, for the total elderly population, there was an increase in diabetes (19.2 to 28.4%), alcohol consumption (2.5 to 3.2%), overweight (52.4 to 60.7%) and obesity (16.8 to 21.8%), and a reduction in the prevalence of smokers (9.4 to 7.4%) and in soft drink consumption (17 to 8.7%). By the interrupted series, between 2015 and 2021, there was stability in the prevalence of diabetes, female smokers, overweight among men, obesity in the total and male population, and soft drink consumption. Conclusion: Over the years, there have been changes and worsening in the indicators analyzed, such as an increase in diabetes, alcohol consumption, overweight, and obesity, which reinforces the importance of continuous monitoring and sustainability programs to promote the health, especially in the context of economic crisis, austerity, and COVID-19 pandemic.

RESUMO Objetivo: Analisar as tendências temporais das prevalências de morbidades e dos fatores de risco e de proteção para as doenças crônicas não transmissíveis em pessoas idosas residentes nas capitais brasileiras entre 2006 e 2021. Métodos: Estudo de série temporal com dados do Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico. Analisaram-se as variáveis: hipertensão arterial; diabetes; tabagismo; excesso de peso; obesidade; consumo de bebidas alcoólicas, refrigerantes, frutas e hortaliças; e prática de atividade física. Empregaram-se o modelo de regressão de Prais-Winsten e a séries temporais interrompidas (de 2006 a 2014 e de 2015 a 2021). Resultados: De 2006 a 2021, para a população total de idosos, houve aumento de diabetes (19,2 para 28,4%), do consumo de álcool (2,5 para 3,2%), do dexcesso de peso (52,4 para 60,7%) e da obesidade (16,8 para 21,8%), e redução do tabagismo (9,4 para 7,4%) e consumo de refrigerantes (17,0 para 8,7%). Pelas séries interrompidas, entre 2015 e 2021, houve estabilidade da prevalência de diabetes, fumantes do sexo feminino, excesso de peso nos homens, obesidade na população total e no sexo masculino e consumo de refrigerante. Conclusão: Ao longo dos anos houve mudanças e piora dos indicadores analisados, como aumento de diabetes, do consumo de álcool, do excesso de peso e da obesidade, o que reforça a importância do monitoramento contínuo e da sustentabilidade de programas de promoção da saúde, especialmente no contexto de crise econômica, austeridade e pandemia decorrente da COVID-19.

COVID-19-Related Testing, Knowledge and Behaviors among Severe and Chronic Non-Communicable Disease Patients in Neno District, Malawi: A Prospective Cohort Study.

COVID-19-related knowledge and behaviors remain essential for controlling the spread of disease, especially among vulnerable patients with advanced, chronic diseases. We prospectively assessed changes over 11 months in COVID-19-related testing, knowledge, and behaviors among patients with non-communicable diseases in rural Malawi using four rounds of telephone interviews between November 2020 to October 2021. The most commonly reported COVID-19-related risks among patients included visiting health facilities (35-49%), attending mass gatherings (33-36%), and travelling outside the district (14-19%). Patients reporting having experienced COVID-like symptoms increased from 30% in December 2020 to 41% in October 2021. However, only 13% of patients had ever received a COVID-19 test by the end of the study period. Respondents answered 67-70% of the COVID-19 knowledge questions correctly, with no significant changes over time. Hand washing, wearing face masks and maintaining a safe distance were the most frequently reported strategies to prevent the spreading of COVID-19. Wearing face masks significantly improved over time (p < 0.001). Although the majority reported accurate knowledge about COVID-19 and enhanced adherence to infection prevention measures over time, patients commonly visited locations where they could be exposed to COVID-19. Government and other stakeholders should increase COVID-19 testing accessibility to primary and secondary facilities.

Current Healthcare Systems in Light of Hyperendemic NCDs and the COVID-19 Pandemic: Time to Change.

Despite the significant achievements of current healthcare systems (CHCSs) in curing or treating several acute conditions, there has been far less success coping with noncommunicable diseases (NCDs), which have complex roots and nonconventional transmission vectors. Owing to the impact of the invisible hyperendemic NCDs and the COVID-19 pandemic, the limitations of CHCSs have been exposed. In contrast, the advent of omics-based technologies and big data science has raised global hope of curing or treating NCDs and improving overall healthcare outcomes. However, challenges related to their use and effectiveness must be addressed. Additionally, while such advancements intend to improve quality of life, they can also contribute the ever-increasing health disparity among vulnerable populations, such as low/middle-income populations, poorly educated people, gender-based violence victims, and minority and indigenous peoples, to name a few. Among five health determinants, the contribution of medical care to individual health does not exceed 11%. Therefore, it is time to implement a new well-being-oriented system complementary or parallel to CHCSs that incorporates all five health determinants to tackle NCDs and unforeseen diseases of the future, as well as to promote cost-effective, accessible, and sustainable healthy lifestyle choices that can reduce the current level of healthcare inequity.

Intervention effects and long-term changes in physical activity and cardiometabolic outcomes among children at risk of noncommunicable diseases in South Africa: a cluster-randomized controlled trial and follow-up analysis.

Introduction: Risk factors for noncommunicable diseases such as insufficient physical activity (PA), overweight or hypertension are becoming increasingly predominant among children globally. While school-based interventions are promising preventive strategies, evidence of their long-term effectiveness, especially among vulnerable populations, is scarce. We aim to assess the short-term effects of the physical and health KaziKidz intervention on cardiometabolic risk factors and the long-term, pre-and post-COVID-19 pandemic changes thereof in high-risk children from marginalized communities. Methods: The intervention was tested in a cluster-randomized controlled trial between January and October 2019 in eight primary schools near Gqeberha, South Africa. Children with overweight, elevated blood pressure, pre-diabetes, and/or borderline dyslipidemia were identified and re-assessed 2 years post-intervention. Study outcomes included accelerometry-measured PA (MVPA), body mass index (BMI), mean arterial pressure (MAP), glucose (HbA1c), and lipid levels (TC to HDL ratio). We conducted mixed regression analyses to assess intervention effects by cardiometabolic risk profile, and Wilcoxon signed-rank tests to evaluate longitudinal changes in the high-risk subpopulation. Results: We found a significant intervention effect on MVPA during school hours for physically inactive children, and among active as well as inactive girls. In contrast, the intervention lowered HbA1c and TC to HDL ratio only in children with glucose or lipid values within the norm, respectively. At follow-up, the intervention effects were not maintained in at-risk children, who showed a decline in MVPA, and an increase in BMI-for-age, MAP, HbA1c and TC to HDL ratio. Conclusion: We conclude that schools are key settings in which to promote PA and improve health; however, structural changes are necessary to ensure that effective interventions reach marginalized school populations and achieve sustainable impact.

Assessment of the WHO non-communicable diseases kit for humanitarian emergencies in South Sudan: a retrospective, prospective, observational study.

BACKGROUND: The WHO Non-Communicable Diseases Kit (NCDK) was developed to support care for non-communicable diseases (NCDs) in humanitarian settings. Targeting primary healthcare, each kit contains medicines and supplies that are forecasted to meet the needs of 10,000 people for 3 months. This study aimed to evaluate the NCDK deployment process, contents, usage and limitations, and to explore its acceptability and effectiveness among healthcare workers (HCWs) in South Sudan. METHODS: This mixed-method observational study captured data from pre-and-post NCDK deployment. Six data collection tools included: (i) contextual analysis, (ii) semi-structured interviews, in addition to surveys measuring/assessing (iii) healthcare workers' knowledge about NCDs, and healthcare workers' perceptions of: (iv) health facility infrastructure, (v) pharmaceutical supply chain, and (vi) NCDK content. The pre- and post-deployment evaluations were conducted in four facilities (October-2019) and three facilities (April-2021), respectively. Descriptive statistics were used for quantitative data and content analysis for open-ended questions. A thematic analysis was applied on interviews findings and further categorized into four predetermined themes. RESULTS: Compared to baseline, two of the re-assessed facilities had improved service availability for NCDs. Respondents described NCDs as a growing problem that is not addressed at a national level. After deployment, the same struggles were intensified with the COVID-19 pandemic. The delivery process was slow and faced delays associated with several barriers. After deployment, poor communications and the "push system" of inventories were commonly perceived by stakeholders, leading to expiry/disposal of some contents. Despite being out-of-stock at baseline, at least 55% of medicines were found to be unused post-deployment and the knowledge surveys demonstrated a need for improving HCWs knowledge of NCDs. CONCLUSIONS: This assessment further confirmed the NCDK role in maintaining continuity of care on a short-term period. However, its effectiveness was dependent on the health system supply chain in place and the capacity of facilities to manage and treat NCDs. Availability of medicines from alternative sources made some of the NCDK medicines redundant or unnecessary for some health facilities. Several learnings were identified in this assessment, highlighting barriers that contributed to the kit underutilization.

Examining the care of noncommunicable diseases at the first level of providing services during the COVID-19 pandemic.

Aim: Providing services for patients with noncommunicable diseases is one of the main responsibilities of health systems. During the COVID-19 pandemic, the care of these patients faced problems. This study investigates the ways of providing optimal care to patients during pandemics like COVID-19. Subject and methods: This study was conducted in 2021 in Tehran province using an analytical cross-sectional method. Six hundred participants were selected for the study. In order to examine the challenges and solutions for receiving services, a questionnaire was completed and its reliability and validity were checked; finally, a telephone interview was completed over a period of 3 months. Results: Among study participants, 68.2% were female, and the highest percentage was in the age group of 50-60 years. Fifty-four percent were illiterate or had primary education, 48.8% had diabetes, 42.8% had high blood pressure, and 8.3% had both diseases. Forty-three percent of the interviewees had not used health care services during the COVID-19 pandemic, the main reason for which was the fear of contracting COVID-19. The outbreak of coronavirus disease had affected the care of noncommunicable diseases for 63% of the interviewees. Conclusion: The fundamental need for changes in the health system was revealed by the COVID-19 pandemic. The need for flexibility in the health system will inevitably arise when similar cases occur, and policymakers and managers should consider necessary measures in this regard. The use of new technologies is one of the ways to replace traditional models.

Characterization of patients with COVID-19 in pinar del rio, March 2020 - March 2021

Introduction: the study of the characteristics of patients with COVID-19 makes it possible to determine risk groups in specific populations and to outline strategies by the institutions to improve the quality of care for these patients. Background: to characterize patients with COVID-19 in Pinar del Rio between March 2020 and March 2021. Methods: an observational, descriptive and cross-sectional study was carried out in patients diagnosed with COVID-19 in the province of Pinar del Rio between March 2020 and March 2021. The sample consisted of 450 patients who met the inclusion and exclusion criteria. Descriptive statistics were used for data analysis. Results: female patients predominated (56%), with a history of arterial hypertension (24,6%). A high incidence of COVID was found in individuals with between two and five chronic non-communicable diseases (40,2%). Of all patients diagnosed with COVID-19, 49% were passive smokers. Conclusions: COVID-19 occurred mainly in patients with several chronic diseases, as well as in those exposed.

Awareness and acceptance of COVID-19 vaccines and associated factors among pharmacy students in Zambia

Aim This study aimed to assess the awareness and acceptance of COVID-19 vaccines and associated factors among pharmacy students in Zambia. Materials and Methods We conducted a cross-sectional study among 326 undergraduate pharmacy students in Lusaka, Zambia, from February to April 2021. Data were analysed using Stata version 16.1. Multivariable logistic regression was used to determine key factors influencing vaccine acceptance. Results Of the 326 participants, 98.8% were aware of the COVID-19 vaccines, but only 24.5% would accept vaccination. Compared to other religions, being of Christian faith was associated with reduced odds of awareness of the COVID-19 vaccine (aOR=0.01, 95% CI: 0.01-0.20). Conversely, factors associated with vaccine acceptance were being male, single and unemployed. Compared to females, male respondents were 86% more likely to accept the vaccine if it was made available (aOR=1.86, 95% CI: 1.10-3.14). In addition, unmarried respondents were 2.65 times as likely to accept vaccination than married respondents (aOR=2.65, 95% CI: 1.06-6.63). Conversely, unemployed respondents were less likely to accept vaccination than their employed counterparts (aOR=0.32, 95% CI: 0.16-0.46). Barriers to the acceptability of the vaccine were possible side effects (78.5%) and scepticism about its effectiveness (10.2%). Conclusion There was significant vaccine hesitancy toward COVID-19 vaccines among Zambian pharmacy students despite their awareness of the vaccines. Health authorities must work collaboratively with training institutions to mitigate vaccine hesitancy, especially with healthcare students being a key part of the future healthcare workforce overseeing disease prevention strategies.

Relevance of Precision Medicine in Public Health Genomics and Global Health Genomics

Precision Medicine (PM) is anticipated to have significant impact on individual health, public health and global health. With advances in sequencing technology, PM is anticipated to have the capacity of predicting health risks and outcomes and improve population health by using genomics and big data, with the aim to provide the right intervention to the right population at the right time – with the goal of improving health for all. In terms of global health, genomics will play a significant role in the prevention and treatment of emerging and reemerging infectious diseases, and prevention and containment of acute and chronic epidemics, and even global pandemics (influenza, tuberculosis, HIV, and COVID-19). Predicting the response to drug treatments, increasing efficacy and avoiding ADRs in public health is also a positive role of PM. However, opponents are worried about the ethical and social concerns, such as the fear of raising the 10/90 gap between developed and developing countries due to PM. With the goal of looking at PM in public health and global health genomics, this chapter will focus on the relevance of PM in the developed and developing countries, while discussing the anticipated ethical and social issues with recommendations to address the concerns. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Increased Cardiovascular Mortality in Ecuador during COVID-19 Pandemic.

Before the COVID-19 pandemic, chronic noncommunicable diseases (NCDs), represented a high burden for low and middle-income countries. Patients with NCDs are at higher risk of COVID-19 and suffer worse clinical outcomes. We present mortality trends for myocardial infarction (AMI), stroke, hypertension (HT), and type-2 diabetes mellitus (T2DM) from 2005 to 2021 in Ecuador. The greatest increase in mortality observed in the pandemic was in AMI, T2DM, and HT. Factors related to COVID-19, health services, and patients with NCDs could contribute to these important increases in mortality.

[Syndemics and non infectious diseases]

The concept of "syndemics" is getting more and more popularity in scientific journals, especially since the end of the first decade of the current century. It relates to the dynamic interaction of synchronous or sequential diseases (whether communicable or not, also including mental diseases), with social and environmental factors, resulting at the end in a worse global outcome. A first article in the same Journal (1) was devoted to infectious diseases, especially COVID-19 and HIV infections. In this second article, we highlight the fact that the concept is also applicable on diseases which are not transmitted by infectious pathogens. The importance of considering action within the field of social determinants of care will be illustrated by a limited selection of examples.

The experiences of older Chinese migrants with chronic diseases during COVID-19 pandemic in Australia

The aim of the study was to understand older Chinese migrants' perceptions of social cohesion and access to health to manage chronic diseases during the COVID-19 pandemic in Australia. This study employed a qualitative descriptive study design. Participants were recruited from a Chinese community organisation in an Australian state. Data were collected via online interviews with participants using Zoom and WeChat Apps. A semistructured interview guide informed by the social determinants of health framework was used in the interview. The data collection period was between August and October, 2020. Thematic analysis was used in data analysis. In total, 24 participants including 17 older Chinese migrants with noncommunicable chronic diseases and seven family carers participated in the study. Of the 17 older Chinese migrants, 10 were male and seven were female. Their mean age was 76 years (ranging from 65 to 86) and they spoke little English. All seven carers were females with a mean age of 61 years (ranging from 35 to 76). Three main themes were identified in the study and described as: increased loneliness, anxiety, and depression;increased difficulties in accessing healthcare services;and various experiences in telehealth. In conclusion, older Chinese-Australians who spoke little English and lived with chronic diseases experienced the loss of their only social capital during the COVID-19 pandemic. They faced language barriers for accessing and utilising primary care to manage their chronic diseases when these care services were changed into telehealth during the COVID-19 pandemic. Findings provide a clear direction for stakeholders to take actions to address the lack of social cohesion and health inequalities for the most vulnerable populations in the community during the COVID-19 pandemic and beyond.

Comparing health service reception in individuals with and without non-communicable diseases before and during the COVID-19 pandemic: Shahrekord cohort study

Introduction: The utilization of health services is an opportunity for using health services by the needy. Since COVID-19 can have significant effects on all life dimensions, including the utilization patterns, especially in patients with non-communicable diseases (NCDs), this study aimed to determine and compare the extent of utilizing health services by individuals with and without NCDs in the Shahrekord cohort study before and during the COVID-19 pandemic. Materials and Methods: The present cross-sectional study was conducted on 760 patients of the age group of 35-70 years in the Shahrekord cohort study, which addressed the urban areas of Shahrekord and the rural regions of Ardel city during two separate periods. For all patients, the questionnaire on benefiting from health services was completed. The data was collected using the telephone interview method and then analyzed using SPSS software. Results: The mean and standard deviation of the age was 44.95..8.65 years in the patients without NCDs and 53.38..8.60 years in those with NCDs (p <0.001). The rates of medical service reception in those without common NCDs before and during the corona epidemic were 3.2% and 15.3%, respectively. In those with common NCDs, the rates were 7.1% and 27.1%, respectively (p <0.001). During the coronavirus epidemic, the average duration of receiving service, duration of service, paid fee, and the frequency of receiving service were longer in the participants with chronic NCDs (P <0.001). Conclusion: The reception of medical services and outpatient services in the two groups of patients with and without NCDs during the coronavirus pandemic increased compared to the pre-pandemic period. This point should be considered as a lesson learned from the epidemic by the health system policymakers and planners to lay the grounds for providing care services, especially for chronic patients during epidemics.

Underused Physical Therapy Services in Primary Care Settings: An Overview

The combined effects of longer life, noncommunicable diseases, and injuries increase the need for rehabilitation services. Although physical therapists' unique skill set on movement-related dysfunction allows for broad contributions to health care, physical therapy (PT) remains underutilized. This article situates the problem within the broader primary care context, focusing on PT's ability to mitigate disability and dysfunction in complex syndromes including pelvic floor incontinence, vertigo, cancer, chronic neuromusculoskeletal pain, and long coronavirus disease (ie, lingering effects after acute coronavirus disease infection passes). The path from PT research to clinical implementation remains dependent on factors beyond research evidence. This overview underscores the need to address this evidence to practice gap.

Clinico-epidemiological correlates of COVID-19 cases - a cross-sectional study from Assam, India

BACKGROUND: Considering the heavy toll taken by COVID- 19 pandemic, the understanding of the epidemiological parameters as well as various risk factors is crucial for future preparedness and tackling the pandemic in a more effective manner. We wanted to study the socio-demographic correlates of COVID -19 cases in Assam, India. Also to find the relationship of clinical status of COVID -19 cases with co- morbidities and with substance use. METHODS: An institution-based cross-sectional study was undertaken from 1st April 2020 to 31st August 2020. Out of the total 12 COVID Care Centres / hospitals that had been established in Kamrup and Kamrup Metro districts of Assam, 6 were randomly selected. A total of 3000 patients were interviewed over telephone by using an android-based application;on or after discharge from the centres, while patient was put on mandatory quarantine. The patients were interviewed on various socio-demographic variables, co-morbidities and substance use behaviour. Categorical variables are expressed as percentages and the continuous variables are expressed as mean +or- standard deviation. t-test and chi-square test were used for continuous and categorical variables respectively. RESULTS: Mean age of moderate and severe cases were 55.10 and 55.9 years respectively. Smoking and use of alcohol were significantly associated with severity of symptoms. Diabetes, hypertension and co-existing lung diseases were found to be associated with status of symptoms. CONCLUSIONS: Epidemiological risk factors like age has to be relooked. Primary prevention on risk factors of non-communicable diseases proved to be crucial in prevention of severity of communicable pandemic like COVID-19. Further studies are required to enhance the knowledge on this aspect.

US Adults Practicing Healthy Lifestyles Before and During COVID-19: Comparative Analysis of National Surveys.

BACKGROUND: Practicing healthy lifestyles can reduce the risk to develop noncommunicable diseases and the related mortality. Studies showed that practicing healthy lifestyles could enhance disease-free life expectancy and preserve bodily functions. However, engagement in healthy lifestyle behavior was suboptimal. OBJECTIVE: This study aimed to define individuals' lifestyle characteristics before and during COVID-19 and determine the factors associated with practicing a healthy lifestyle. This cross-sectional study was conducted using data from the 2019 and 2021 Behavioral Risk Factor Surveillance System surveys. METHODS: US individuals aged ≥18 years were interviewed via phone call. Healthy lifestyles were assessed through corresponding questions regarding the maintenance of optimal body weight, physical activity, daily consumption of at least five portions of fruits and vegetables, current smoking status, and alcohol consumption. Missing data were imputed using a package in the R statistical software. The effects of practicing a healthy lifestyle on cases without missing data and those with imputation were reported. RESULTS: There were 550,607 respondents (272,543 and 278,064 from 2019 and 2021, respectively) included in this analysis. The rates of practicing a healthy lifestyle were 4% (10,955/272,543) and 3.6% (10,139/278,064) in 2019 and 2021, respectively. Although 36.6% (160,629/438,693) of all 2021 respondents had missing data, the results of the logistic regression analysis for cases without missing data and those with imputation were similar. Of the cases with imputation, women (odds ratio [OR] 1.87) residing in urban areas (OR 1.24) with high education levels (OR 1.73) and good or better health status (OR 1.59) were more likely to practice healthier lifestyles than young individuals (OR 0.51-0.67) with a low household income (OR 0.74-0.78) and chronic health conditions (OR 0.48-0.74). CONCLUSIONS: A healthy lifestyle should be strongly promoted at the community level. In particular, factors associated with a low rate of practice of healthy lifestyles should be targeted.

The Case for Integrating Health Systems to Manage Noncommunicable and Infectious Diseases in Low- and Middle-Income Countries: Lessons Learned From Zambia.

Noncommunicable diseases (NCDs) are the leading cause of death in the world, and 80% of all NCD deaths occur in low- and middle-income countries (LMICs). The COVID-19 pandemic has demonstrated that patients with NCDs are at increased risk of becoming severely ill from the virus. Disproportionate investment in vertical health programs can result in health systems vulnerable to collapse when resources are strained, such as during pandemics. Although NCDs are largely preventable, globally there is underinvestment in efforts to address them. Integrating health systems to collectively address NCDs and infectious diseases through a wide range of services in a comprehensive manner reduces the economic burden of healthcare and strengthens the healthcare system. Health system resiliency is essential for health security. In this article, we provide an economically sound approach to incorporating NCDs into routine healthcare services in LMICs through improved alignment of institutions that support prevention and control of both NCDs and infectious diseases. Examples from Zambia's multisector interventions to develop and support a national NCD action plan can inform and encourage LMIC countries to invest in systems integration to reduce the social and economic burden of NCDs and infectious diseases.